DERIVADOS DE DIACIL-HIDRAZINA

DERIVADOS DE DIACIL-HIDRAZINA

Diacylhydrazine derivatives of general formula (I)wherein X, Y, Z, R , and R are as defined herein, and their physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be used to combat thromboses, myocardial infarcts, coronary cardiac diseases, arteriosclerosis, inflamma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SIMON GOODMAN, GUNTER HOLZEMANN, GABOR SULYOK, CHRISTOPH GIBSON, HORST KESSLER, -DR
Format: Patent
Sprache:por
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Diacylhydrazine derivatives of general formula (I)wherein X, Y, Z, R , and R are as defined herein, and their physiologically acceptable salts or solvates thereof, are integrin inhibitors and can be used to combat thromboses, myocardial infarcts, coronary cardiac diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections, and restenosis following angioplasty or during pathological processes that are maintained or propagated by angiogenesis.