HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME

Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo are described. Methods of preparing said conjugates and therapeutic compositions are also described. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly us...

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Bibliographische Detailangaben
Hauptverfasser: JULIA L. GREENSTEIN, BARBARA S. FOX, STEPHEN P. POWERS, PHILIP A. SWAIN, MARK A. EXLEY, MALCOLM L. GEFTER
Format: Patent
Sprache:eng ; por
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Zusammenfassung:Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo are described. Methods of preparing said conjugates and therapeutic compositions are also described. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of a drug addiction. The therapeutic composition is suitable for co-therapy with other conventional drugs. Passive immunization using antibodies raised against the hapten-carrier conjugates of the invention are also described.