Novel peptide useful as intermediate for angiotensin transferase inhibitor lisinopril - can be prepd on large scale from stable starting materials

Novel peptide useful as intermediate for angiotensin transferase inhibitor lisinopril - can be prepd on large scale from stable starting materials

A peptide of formula (II) or its salt is new: Also claimed is the prepn. of lisinopril of formula (I) comprising subjecting (II) to hydrogenolysis to give (Ia), followed by hydrolysis to give (I). -

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Bibliographische Detailangaben
Hauptverfasser: LAJOS KOVACS, JANOS FISCHER, LASZLO DOBAY, TAMAS FODOR, TAMAS UBERHARDT, BELA STEFKO, GEZA IVANYI
Format: Patent
Sprache:eng ; por
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:A peptide of formula (II) or its salt is new: Also claimed is the prepn. of lisinopril of formula (I) comprising subjecting (II) to hydrogenolysis to give (Ia), followed by hydrolysis to give (I). -