FREEZE DRIED LOW HYGROSCOPICITY ACTIVE POWDER COMPOSITIONS

A method of forming an inhalable powder composition including combining sugar or a sugar alcohol with an active agent and a liquid carrier to form a liquid mixture, and freeze drying the liquid mixture to form crystalline dry composition, and then milling the crystalline dry composition to from crys...

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Bibliographische Detailangaben
Hauptverfasser: SPADARO, FABIANA, ZUBER, GERARD
Format: Patent
Sprache:eng ; pol
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Beschreibung
Zusammenfassung:A method of forming an inhalable powder composition including combining sugar or a sugar alcohol with an active agent and a liquid carrier to form a liquid mixture, and freeze drying the liquid mixture to form crystalline dry composition, and then milling the crystalline dry composition to from crystalline dry powder particles having a particle size of about 5 micrometers or less.