6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER
Compounds of formula (I):wherein Het, Het1, Het2, A4, A5, Z1, R1, R2 and R3 are as defined in the description. Medicaments.
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| creator | TIMÁRI, MÁTYÁS PÁL STARCK, JÉRÔME-BENOIT MURRAY, JAMES BROOKE HERNER, ANDRÁS MARAGNO, ANA LETICIA COLLAND, FRÉDÉRIC NOVAK, TIBOR DODSWORTH, MARK PHILIP WEBB, PAUL SANDERS, EMMA BEDFORD, SIMON PACZAL, ATTILA CHANRION, MAÏA KOTSCHY, ANDRÁS DAVIDSON, JAMES EDWARD PAUL |
| description | Compounds of formula (I):wherein Het, Het1, Het2, A4, A5, Z1, R1, R2 and R3 are as defined in the description. Medicaments. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER |
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