6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER

Compounds of formula (I):wherein Het, Het1, Het2, A4, A5, Z1, R1, R2 and R3 are as defined in the description. Medicaments.

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Hauptverfasser: TIMÁRI, MÁTYÁS PÁL, STARCK, JÉRÔME-BENOIT, MURRAY, JAMES BROOKE, HERNER, ANDRÁS, MARAGNO, ANA LETICIA, COLLAND, FRÉDÉRIC, NOVAK, TIBOR, DODSWORTH, MARK PHILIP, WEBB, PAUL, SANDERS, EMMA, BEDFORD, SIMON, PACZAL, ATTILA, CHANRION, MAÏA, KOTSCHY, ANDRÁS, DAVIDSON, JAMES EDWARD PAUL
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:Compounds of formula (I):wherein Het, Het1, Het2, A4, A5, Z1, R1, R2 and R3 are as defined in the description. Medicaments.