ANTI-HER2 ANTIBODY DRUG CONJUGATE PHARMACEUTICAL PREPARATION

A pharmaceutical preparation comprising a mixture of a nonreducing sugar, a recombinant humanized anti-Her2 monoclonal antibody-MMAE conjugate, and a surfactant. The pharmaceutical preparation has the characteristics of reducing particulate matters, reducing aggregate formation, improving the stabil...

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Bibliographische Detailangaben
Hauptverfasser:	FANG, JIANMIN, BAO, QIANJING, LI, ZHUANGLIN, XU, QIAOYU, YAO, XUEJING
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A pharmaceutical preparation comprising a mixture of a nonreducing sugar, a recombinant humanized anti-Her2 monoclonal antibody-MMAE conjugate, and a surfactant. The pharmaceutical preparation has the characteristics of reducing particulate matters, reducing aggregate formation, improving the stability of a conjugate, improving the appearance of freeze-dried powder, etc.