AMLOPIDINE BEZYLATE TABLETS WITH IMPROVED STABILITY

AMLOPIDINE BEZYLATE TABLETS WITH IMPROVED STABILITY

The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 8...

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Bibliographische Detailangaben
Hauptverfasser: FEKETE PAL, LONKAINE MAGYAR OLGA, LEVENTISZNE HUSZAR MAGDOLNA, TOMPE PETER, SZENTGROTI PALNE, THUROCZI PALNE, KIRALYNE IGNACZ MARIA, GORA LASZLONE
Format: Patent
Sprache:eng ; pol
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Beschreibung
Zusammenfassung:The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 87 to 94 % by weight of microcrystalline cellulose, 1-5 % by weight of a disintegrating agent, 0.5 to 1.5 % by weight of a lubricant and 0.2 to 1.0 % by weight of colloidal silicon dioxide. The invention also relates to a process for the preparation of the said tablets.