PROCESS FOR PREPARING N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE BY REACTING THE CORRESPONDING AMINE WITH A 3-HALO-PROPIONYL CHLORIDE

The present invention provides an improved process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors. Additionally...

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Bibliographische Detailangaben
Hauptverfasser: PARK, SU-MIN, LIM, JONGUL, LEE, SEONG-RAN, KHOO, JA-HEOUK, JU, HYUN, OH, SANG-HO, SHIN, WOO-SEOB, PARK, DAE-GYU, HWANG, YOON-AH
Format: Patent
Sprache:eng ; pol
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