TRANSDERMAL DRUG DELIVERY DEVICES COMPRISING (R)-(Z)-1-AZABICYCLO(2.2.1)HEPTAN-3-ONE, 0-(3(3-METHOXYPHENYL)-2-PROPYNYL)OXIME

TRANSDERMAL DRUG DELIVERY DEVICES COMPRISING (R)-(Z)-1-AZABICYCLO(2.2.1)HEPTAN-3-ONE, 0-(3(3-METHOXYPHENYL)-2-PROPYNYL)OXIME

Systems and devices for the transdermal delivery of the compound (R) (Z) 1 azabicyclo[2.2.1]heptan 3 one, 0 [3(3 methoxyphenyl) 2 propynyl]oxime are disclosed. These devices include a drug in adhesive reservoir layer and a skin contacting adhesive layer in which the skin contacting adhesive layer ac...

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Bibliographische Detailangaben
1. Verfasser: DREYER STEVE J
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Systems and devices for the transdermal delivery of the compound (R) (Z) 1 azabicyclo[2.2.1]heptan 3 one, 0 [3(3 methoxyphenyl) 2 propynyl]oxime are disclosed. These devices include a drug in adhesive reservoir layer and a skin contacting adhesive layer in which the skin contacting adhesive layer acts as a rate controlling membrane. These devices also include a drug in adhesive reservoir layer and a skin contacting adhesive, where a membrane is placed between the two adhesive layers. The compound is a muscarinic agonist, useful in the treatment of a variety of cognitive disorders, including Alzheimer s Disease.