PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES

PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES

Compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens are disclosed. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VIsE protein. Also provided are devices, methods, and kits comp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BLEILE, DENNIS M, MEHRA, RAJESH K, ARON, KENNETH P, WALKER, JEREMY, CUESICO, CRISTINA
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:Compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens are disclosed. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VIsE protein. Also provided are devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.