TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS

The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical composit...

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Hauptverfasser:	AIZPURUA IPARRAGUIRRE, JESÚS MARÍA, TORAL OJEDA, IVÁN, LÓPEZ DE MUNAIN ARREGI, ADOLFO JOSÉ, VALLEJO ILLARRAMENDI, AINARA, FERRÓN CELMA, PABLO, MIRANDA MURUA, JOSÉ IGNACIO, IRASTORZA EPELDE, AITZIBER, ALDANONDO ARISTIZABAL, GARAZI
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.