VACCINES WITH THE LTB ADJUVANT

The present invention relates to a vaccine containing at least one immunogen and an adjuvanting amount of B subunits of heat-labile enterotoxin characteristic of E. coli isolated from a non-human source. This vaccine is particularly suitable for induction of a protective response against said immuno...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DE HAAN LOLKE, AGSTERIBBE ETIENNE, VERWEIJ WILLEM RONALD, VAN SCHARRENBURG GUSTAAF JOHAN MARIE, BRANDS RUDI, WILSCHUT JAN CHRISTIAAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a vaccine containing at least one immunogen and an adjuvanting amount of B subunits of heat-labile enterotoxin characteristic of E. coli isolated from a non-human source. This vaccine is particularly suitable for induction of a protective response against said immunogen upon mucosal (e.g. intra-nasal) administration.