MULTIVALENT AND MULTISPECIFIC DR5-BINDING FUSION PROTEINS

MULTIVALENT AND MULTISPECIFIC DR5-BINDING FUSION PROTEINS

The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.

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Bibliographische Detailangaben
Hauptverfasser: TIMMER, JOHN C, RAZAI, AMIR S, ECKELMAN, BRENDAN P, DEVERAUX, QUINN, JONES, KYLE S, HUSSAIN, ABRAHIM, WILLIS, KATELYN M
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.