METHOD OF OBTAINING A DERIVATIVE OF DIHYDROPYRIDINE

METHOD OF OBTAINING A DERIVATIVE OF DIHYDROPYRIDINE

A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-met...

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Hauptverfasser: KRASZNAI GYORGY, LAX KOVANYI GYORGYI, BLASKO GABOR, DONATH VERECZKEY GYORGY, NAGY KALMAN, TOMPE PETER, BOZSING DANIEL, SIMIG GYULA, NEMETH NORBERT, NEMET GABOR
Format: Patent
Sprache:eng
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Zusammenfassung:A subject matter of the invention is a process for preparing 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(aminoethoxy)-methylÜ-4--Ä2''-(chloro)-phen ylÜ-6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ benzenesulfonic acid salt of Formula in which 3-ÄethylÜ-5-ÄmethylÜ-2-Ä2'-(yl)-ethoxy-methylÜ-4-Ä2''-(chloro)-phenylÜ -6-ÄmethylÜ-1,4-di-ÄhydroÜ-pyridine-3,5-di-ÄcarboxylateÜ hexaminium iodide of Formula is reacted with benzenesulfonic acid of Formula Several variants comprise also reactions for preparing intermediates leading to the said end product. A further subject matter of the invention are intermediates for preparing the said end product.