9-MEMBERED FUSED RING DERIVATIVE
The purpose of the present invention is to provide novel compounds having ACC2 selective inhibitory activity. In addition, the present invention provides a pharmaceutical composition comprising the compound. A compound of Formula: or its pharmaceutically acceptable salt, wherein, R 1 is substituted...
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Format: | Patent |
Sprache: | eng ; pol |
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Zusammenfassung: | The purpose of the present invention is to provide novel compounds having ACC2 selective inhibitory activity. In addition, the present invention provides a pharmaceutical composition comprising the compound. A compound of Formula:
or its pharmaceutically acceptable salt,
wherein, R 1 is substituted or unsubstituted fused aromatic heterocyclyl represented by Formula:
wherein,
ring B is 5-membered ring, ring C is 6-membered ring;
ring A is substituted or unsubstituted non-aromatic carbocycle or the like;
-L 1 - is -O-(CR 6 R 7 )m- or the like;
-L 2 - is -O-(CR 6 R 7 )n- or the like;
each R 6 is independently hydrogen or the like;
each R 7 is independently hydrogen or the like;
each m is independently an integer of 0, 1, 2 or 3;
each n is independently an integer of 1, 2 or 3;
R 2 is substituted or unsubstituted alkyl;
R 3 is hydrogen or substituted or unsubstituted alkyl;
R 4 is substituted or unsubstituted alkylcarbonyl or the like. |
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