POLYMORPHS OF THE PRECURSOR OF THE DRUG 6-N-(L-ALA-L-ALA)-THROWAFLOXACIN

PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - P...

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Hauptverfasser:	NORRIS TIMOTHY, ALLEN DOUGLAS JOHN MELDRUM, MCGARRY JAMES JOHN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	PCT No. PCT/IB96/00653 Sec. 371 Date Jan. 30, 1998 Sec. 102(e) Date Jan. 30, 1998 PCT Filed Jul. 5, 1996 PCT Pub. No. WO97/08191 PCT Pub. Date Mar. 6, 1997The invention relates to a monohydrate polymorph PII.M of a compound of the formula exhibiting the following X-ray powder diffraction pattern - Peak No. 1 2 3 4 5 6 7 8 - 2- theta -( DEG ) Cu 3.6 7.3 13.7 14.5 17.1 21.) 23.6 26.7 - d space 24.2 12.2 6.5 6.1 5.2 4.2 3.8 3.3 - The invention also relates to methods of preparing the above compound, pharmaceutical compositions containing the above compound, and methods of treating bacterial infections by administering the above compound.