DERIVATIVES OF 1-[-(3,4-DIHYDRO-2-NAPHTALENYL]ALKYL]-CYCLOAMINE,METHOD OF OBTAINING THEM AND PHARMACEUTIC PRPARATION CONTAINING SUCH DERIVATIVES

1-Ä omega -(3,4-Dihydro-2-naphthalenyl)alkylÜ cyclic amine derivatives represented by general formula (I) and salts and N-oxide derivatives thereof, wherein R and R represent each hydrogen, halogeno, hydroxy, alkyl, alkoxy, hydroxymethyl, etc., or R and R form together methylenedioxy, trimethylene,...

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Hauptverfasser: HINO KATSUHIKO, SHIMIZU ISAO, KAWASHIMA KATSUYOSHI, KANEHIRA AKI, KAI NAOKI, AKIYAMA KAZUHISA, MORIE TOSHIYA
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creator HINO KATSUHIKO
SHIMIZU ISAO
KAWASHIMA KATSUYOSHI
KANEHIRA AKI
KAI NAOKI
AKIYAMA KAZUHISA
MORIE TOSHIYA
description 1-Ä omega -(3,4-Dihydro-2-naphthalenyl)alkylÜ cyclic amine derivatives represented by general formula (I) and salts and N-oxide derivatives thereof, wherein R and R represent each hydrogen, halogeno, hydroxy, alkyl, alkoxy, hydroxymethyl, etc., or R and R form together methylenedioxy, trimethylene, etc.; R represents hydrogen, etc.; R represents hydrogen, hydroxy, alkyl, etc.; R represents hydrogen, alkyl, etc.; p is an integer of from 2 to 6; and q is an integer of from 3 to 7; excluding the case where R , R , R , R and R are all hydrogen, p is 2 and q is 5. The compounds have a potent effect of suppressing urinary reflex and thus are useful as a remedy for frequent urination and urinary incontinence.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DERIVATIVES OF 1-[-(3,4-DIHYDRO-2-NAPHTALENYL]ALKYL]-CYCLOAMINE,METHOD OF OBTAINING THEM AND PHARMACEUTIC PRPARATION CONTAINING SUCH DERIVATIVES
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