DERIVATIVES OF 1-[-(3,4-DIHYDRO-2-NAPHTALENYL]ALKYL]-CYCLOAMINE,METHOD OF OBTAINING THEM AND PHARMACEUTIC PRPARATION CONTAINING SUCH DERIVATIVES

1-Ä omega -(3,4-Dihydro-2-naphthalenyl)alkylÜ cyclic amine derivatives represented by general formula (I) and salts and N-oxide derivatives thereof, wherein R and R represent each hydrogen, halogeno, hydroxy, alkyl, alkoxy, hydroxymethyl, etc., or R and R form together methylenedioxy, trimethylene,...

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Hauptverfasser: HINO KATSUHIKO, SHIMIZU ISAO, KAWASHIMA KATSUYOSHI, KANEHIRA AKI, KAI NAOKI, AKIYAMA KAZUHISA, MORIE TOSHIYA
Format: Patent
Sprache:eng
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Zusammenfassung:1-Ä omega -(3,4-Dihydro-2-naphthalenyl)alkylÜ cyclic amine derivatives represented by general formula (I) and salts and N-oxide derivatives thereof, wherein R and R represent each hydrogen, halogeno, hydroxy, alkyl, alkoxy, hydroxymethyl, etc., or R and R form together methylenedioxy, trimethylene, etc.; R represents hydrogen, etc.; R represents hydrogen, hydroxy, alkyl, etc.; R represents hydrogen, alkyl, etc.; p is an integer of from 2 to 6; and q is an integer of from 3 to 7; excluding the case where R , R , R , R and R are all hydrogen, p is 2 and q is 5. The compounds have a potent effect of suppressing urinary reflex and thus are useful as a remedy for frequent urination and urinary incontinence.