METHODS FOR THE PREPARATION OF RIBOSIDES

Provided are methods of preparing compounds and pharmaceutical compositions for treating Filoviridae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.A method preparing a compound of...

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Hauptverfasser:	ROSS, BRUCE, LEW, WILLARD, TADEUS, CLARISSA, CHTELININE, ANDREI, CAMPAGNA, SILVIO, GAO, DETIAN, VIEIRA, TIAGO, NEVILLE, SEAN TIMOTHY, WALTMAN, ANDREW W, SCOTT, ROBERT WILLIAM, BADALOV, PAVEL ROBERTOVICH, WANG, XIANGHONG, BRAK, KATRIEN, HEUMANN, LARS V, YU, CHIA-YUN, SIEGEL, DUSTIN, RUEDEN, ERICK, WOLFE, LYDIA, WHITCOMB, MARK CHARLES, DOERFFLER, EDWARD, HOANG, BRITTANIE, STEVENS, ANDREW C, AXT, STEVEN DONALD, MILBURN, ROBERT RONALD, FRICK, MORIN MAE
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	Provided are methods of preparing compounds and pharmaceutical compositions for treating Filoviridae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.A method preparing a compound of Formula (XI-a2) is disclosed: