CYCLOALKYL-LINKED DIHETEROCYCLE DERIVATIVES

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R-R, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals....

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Bibliographische Detailangaben
Hauptverfasser:	GREASLEY, SAMANTHA ELIZABETH, RICHTER, DANIEL TYLER, HUANG, QINHUA, NARASIMHAN, LAKSHMI SOURIRAJAN, KANIA, ROBERT STEVEN, RICHARDSON, PAUL FRANCIS, KUNG, PEI-PEI, HOFFMAN, ROBERT LOUIS, COLLINS, MICHAEL RAYMOND, LINTON, MARIA ANGELICA, SMITH, GRAHAM, BURNS, AARON CRAIG
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R-R, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.