POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS

POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS

Provided are compounds of formula (III), and the use of compounds of formula (III) in methods of treatment, such as methods of treating a microbial infection. The compounds of formula (III) is: where -R15 is an amino-containing group: and -R1, -R2, -R3, -R4, -R8, -RA, Q, -R16, -R17 are as described...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BROWN, PAMELA, STANWAY, STEVEN JAMES, MOSS, STEPHEN FREDERICK, DAWSON, MICHAEL, SIMONOVIC, MONA, DUPERCHY, ESTHER, BOAKES, STEVEN, WILSON, ANTOINETTE
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided are compounds of formula (III), and the use of compounds of formula (III) in methods of treatment, such as methods of treating a microbial infection. The compounds of formula (III) is: where -R15 is an amino-containing group: and -R1, -R2, -R3, -R4, -R8, -RA, Q, -R16, -R17 are as described in further detail in the description.