PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES

A process is described for the synthesis of pyrazoles having general formula (I) which comprises the steps of mixing a compound having general formula (II) and a 1,2-disubstituted hydrazine having general formula (III) to form a reaction intermediate having general formula (IV) and the reaction mixt...

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Hauptverfasser: MEAZZA GIOVANNI, SILLANI LAURA, MEREGHETTI PIERANGELO, FORGIA DANIELE
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:A process is described for the synthesis of pyrazoles having general formula (I) which comprises the steps of mixing a compound having general formula (II) and a 1,2-disubstituted hydrazine having general formula (III) to form a reaction intermediate having general formula (IV) and the reaction mixture obtained in step i), in an acid environment, cyclizes to form a pyrazole having general formula (I), according to reaction scheme 1 Scheme 1.