THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS

The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...

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Bibliographische Detailangaben
Hauptverfasser:	DOMÍNGUEZ CORREA JUAN MANUEL, RODRÍGUEZ SALGUERO BEATRIZ, SÁNCHEZ-QUESADA JORGE, MARTÍNEZ MONTERO OLGA, PALOMO NICOLAU FRANCISCO, DE CRISTOBAL BLANCO JAVIER, MEDINA PADILLA MIGUEL, HERRERO SANTOS SUSANA, PÉREZ DE LA CRUZ MORENO MARÍA ÁNGELES, LÓPEZ OGALLA JAVIER, FUERTES HUERTA ANA
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.