PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Bibliographische Detailangaben
Hauptverfasser: DEMATTEI, JOHN, NEUBERT-LANGILLE, BOBBIANA, BOTFIELD, MARTYN C, KRUEGER, BRIAN R, ROPER, STEFANIE, ZLOKARNIK, GREGOR, RYAN, MICHAEL, LOOKER, ADAM R, GROOTENHUIS, PETER D.J, TRUDEAU, MARTIN, YAP, DAHRIKA MILFRED LAO, VAN GROOR, FREDERICK F
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.