COMPOSITIONS AND METHODS FOR NUCLEIC ACID HYBRIDIZATION

Polynucleotides having a first polynucleotide segment contiguous with a second polynucleotide segment that is downstream to the first, wherein the sequence of the first polynucleotide segment is complementary to the sequence of a first probe segment of a probe for detection of a target nucleic acid...

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Bibliographische Detailangaben
Hauptverfasser: SCHOUEST, KATHERINE, WRONSKA, DANUTA
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:Polynucleotides having a first polynucleotide segment contiguous with a second polynucleotide segment that is downstream to the first, wherein the sequence of the first polynucleotide segment is complementary to the sequence of a first probe segment of a probe for detection of a target nucleic acid sequence, wherein the sequence of the second polynucleotide segment is complementary to the sequence of a second probe segment of the probe, wherein the second probe segment is downstream to the first probe segment, are provided. The polynucleotides may be employed with dual-labeled probes (DLPs) in assays for the detection of the target nucleic acid sequences.