HYPOALLERGEN

The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JYLHÄ, SIRPA, TAKKINEN, KRISTIINA, ROUVINEN, JUHA, NIEMI, MERJA, SÖDERLUND, HANS, JÄNIS, JANNE, LAUKKANEN, MARJA-LEENA, HOLKERI, HEIDI
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formulations comprising such polypeptides; the use of such formulations; and to methods of vaccination against birch pollen allergy.