TABLET FORMULATIONS OF NERATINIB MALEATE

The invention provides a high strength neratinib tablet and a method of its manufacturing comprising spraying intragranular components of a granulation comprising neratinib maleate, fillers, disintegrants and glidants, with a surface modifying agent and combining them with extragranular components c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	NAGI, ARWINDER SINGH, GHOSH, KRISHNENDU, MAHMUD, MAINUDDIN, ASHRAF, MUHAMMAD, GOOLCHARRAN, CHIMANLALL
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention provides a high strength neratinib tablet and a method of its manufacturing comprising spraying intragranular components of a granulation comprising neratinib maleate, fillers, disintegrants and glidants, with a surface modifying agent and combining them with extragranular components comprising fillers, disintegrants and lubricants.