New peptide derivatives of platelet-derived growth factor (PDGF), method for obtaining, pharmaceutical composition and application

The present invention relates to novel peptide derivatives of platelet derived growth factor (PDGF) and a method for their preparation.In addition, the invention relates to a pharmaceutical composition containing the new compounds and the use of these compounds as a treatment for skin problems that...

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Hauptverfasser: KARPOWICZ, PRZEMYSŁAW, DZIERŻYŃSKA, MARIA, PIKUŁA, MICHAŁ, MADANECKI, PIOTR, JANUS, ŁUKASZ, WARDOWSKA, ANNA, DEPTUŁA, MILENA, KASPRZYKOWSKI, FRANCISZEK, SKOWRON, PIOTR, RODZIEWICZ-MOTOWIDŁO, SYLWIA, SACHADYN, PAWEŁ, SAWICKA, JUSTYNA, FILIPOWICZ, NATALIA, PIOTROWSKI, ARKADIUSZ, CZUPRYN, ARTUR, SOSNOWSKI, PAWEŁ, MIECZKOWSKA, ALINA, MUCHA, PIOTR, SAS, PIOTR
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Sprache:eng ; pol
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creator KARPOWICZ, PRZEMYSŁAW
DZIERŻYŃSKA, MARIA
PIKUŁA, MICHAŁ
MADANECKI, PIOTR
JANUS, ŁUKASZ
WARDOWSKA, ANNA
DEPTUŁA, MILENA
KASPRZYKOWSKI, FRANCISZEK
SKOWRON, PIOTR
RODZIEWICZ-MOTOWIDŁO, SYLWIA
SACHADYN, PAWEŁ
SAWICKA, JUSTYNA
FILIPOWICZ, NATALIA
PIOTROWSKI, ARKADIUSZ
CZUPRYN, ARTUR
SOSNOWSKI, PAWEŁ
MIECZKOWSKA, ALINA
MUCHA, PIOTR
SAS, PIOTR
description The present invention relates to novel peptide derivatives of platelet derived growth factor (PDGF) and a method for their preparation.In addition, the invention relates to a pharmaceutical composition containing the new compounds and the use of these compounds as a treatment for skin problems that are difficult to heal and skin lesions of various aetiologies, including wounds resulting from venous insufficiency, tissue ischemia, atherosclerosis, diabetes, neurological and inflammatory diseases, surgical wounds, wounds after chemo-and/or radiotherapy treatments and other pathological conditions.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title New peptide derivatives of platelet-derived growth factor (PDGF), method for obtaining, pharmaceutical composition and application
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