New peptide derivatives of platelet-derived growth factor (PDGF), method for obtaining, pharmaceutical composition and application

The present invention relates to novel peptide derivatives of platelet derived growth factor (PDGF) and a method for their preparation.In addition, the invention relates to a pharmaceutical composition containing the new compounds and the use of these compounds as a treatment for skin problems that...

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Hauptverfasser: KARPOWICZ, PRZEMYSŁAW, DZIERŻYŃSKA, MARIA, PIKUŁA, MICHAŁ, MADANECKI, PIOTR, JANUS, ŁUKASZ, WARDOWSKA, ANNA, DEPTUŁA, MILENA, KASPRZYKOWSKI, FRANCISZEK, SKOWRON, PIOTR, RODZIEWICZ-MOTOWIDŁO, SYLWIA, SACHADYN, PAWEŁ, SAWICKA, JUSTYNA, FILIPOWICZ, NATALIA, PIOTROWSKI, ARKADIUSZ, CZUPRYN, ARTUR, SOSNOWSKI, PAWEŁ, MIECZKOWSKA, ALINA, MUCHA, PIOTR, SAS, PIOTR
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:The present invention relates to novel peptide derivatives of platelet derived growth factor (PDGF) and a method for their preparation.In addition, the invention relates to a pharmaceutical composition containing the new compounds and the use of these compounds as a treatment for skin problems that are difficult to heal and skin lesions of various aetiologies, including wounds resulting from venous insufficiency, tissue ischemia, atherosclerosis, diabetes, neurological and inflammatory diseases, surgical wounds, wounds after chemo-and/or radiotherapy treatments and other pathological conditions.