IMMUNOGLOBULIN VARIABLE REGION CASSETTE EXCHANGE

A library of hybrid V-regions comprising members that have a diversity of V-regions, wherein a member has at least a minimal essential binding specificity determinant (MEBSD) of a CDR from a reference antibody and at least one exchange cassette from an antibody repertoire, with the proviso that the...

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Bibliographische Detailangaben
Hauptverfasser:	BEBBINGTON, CHRISTOPHER, YARRANTON, GEOFFREY, LUEHRSEN, KENNETH
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A library of hybrid V-regions comprising members that have a diversity of V-regions, wherein a member has at least a minimal essential binding specificity determinant (MEBSD) of a CDR from a reference antibody and at least one exchange cassette from an antibody repertoire, with the proviso that the exchange cassette has less than three framework regions.