NOVEL PROSTAGLANDIN I2 DERIVATIVE

Disclosed is a novel prostaglandin I 2 derivative which is different from known PGI 2 analogs, or a pharmaceutically acceptable salt thereof. More specifically disclosed is a 7,7-difluoro-PGI 2 derivative (formula (1)), particularly wherein R 1 and R 2 are each independently a hydrogen atom or a str...

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Bibliographische Detailangaben
Hauptverfasser:	KONISHI, KATSUHIKO, AMAKAWA, MASAHIRO, MATSUMURA, YASUSHI, TERADAIRA, SHIN, MURATA, TAKAHIKO
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed is a novel prostaglandin I 2 derivative which is different from known PGI 2 analogs, or a pharmaceutically acceptable salt thereof. More specifically disclosed is a 7,7-difluoro-PGI 2 derivative (formula (1)), particularly wherein R 1 and R 2 are each independently a hydrogen atom or a straight chain alkyl group having a carbon number of 1 - 3, and R 3 is a hydrogen atom, an alkyl group having a carbon number of 1 - 4, an alkoxyalkyl group, an aryl group, a halogen atom or a haloalkyl group.