Application of the bacitracin antibiotic for the hydrolytic degradation of RNA

Application of the bacitracin antibiotic for the hydrolytic degradation of RNA

The subject of the present invention is the use of bacitracin for the hydrolytic degradation of RNA, occurring at guanosine residues, preferably in single-stranded RNA regions, and occurring without the involvement of transition metal ions. According to the invention, it is possible to use bacitraci...

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Hauptverfasser: BŁASZCZYK LESZEK, KASPROWICZ ALEKSANDRA, WRZESIŃSKI JAN, CIESIOŁKA JERZY, STOKOWA-SOŁTYS KAMILA, NAGAJ JUSTYNA, JEŻOWSKA-BOJCZUK MAŁGORZATA, SZCZEPANIK WOJCIECH
Format: Patent
Sprache:eng ; pol
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator BŁASZCZYK LESZEK
KASPROWICZ ALEKSANDRA
WRZESIŃSKI JAN
CIESIOŁKA JERZY
STOKOWA-SOŁTYS KAMILA
NAGAJ JUSTYNA
JEŻOWSKA-BOJCZUK MAŁGORZATA
SZCZEPANIK WOJCIECH
description The subject of the present invention is the use of bacitracin for the hydrolytic degradation of RNA, occurring at guanosine residues, preferably in single-stranded RNA regions, and occurring without the involvement of transition metal ions. According to the invention, it is possible to use bacitracin according to a mechanism dependent on the degradation of undesirable RNA, different than that stipulated to-date.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Application of the bacitracin antibiotic for the hydrolytic degradation of RNA
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