Application of the bacitracin antibiotic for the hydrolytic degradation of RNA

The subject of the present invention is the use of bacitracin for the hydrolytic degradation of RNA, occurring at guanosine residues, preferably in single-stranded RNA regions, and occurring without the involvement of transition metal ions. According to the invention, it is possible to use bacitraci...

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Bibliographische Detailangaben
Hauptverfasser:	BŁASZCZYK LESZEK, KASPROWICZ ALEKSANDRA, WRZESIŃSKI JAN, CIESIOŁKA JERZY, STOKOWA-SOŁTYS KAMILA, NAGAJ JUSTYNA, JEŻOWSKA-BOJCZUK MAŁGORZATA, SZCZEPANIK WOJCIECH
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The subject of the present invention is the use of bacitracin for the hydrolytic degradation of RNA, occurring at guanosine residues, preferably in single-stranded RNA regions, and occurring without the involvement of transition metal ions. According to the invention, it is possible to use bacitracin according to a mechanism dependent on the degradation of undesirable RNA, different than that stipulated to-date.