(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-PIPERAZINES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATION

Inhibitors of LIM kinase 2 of the following formula are disclosed, along with pharmaceutical compositions comprising them and methods of their use, in particular for treatment of inflammatory and cancerous and ocular diseases. X is O or NR A ; A is cycloalkyl, aryl or heterocyclyl; R A is hydrogen,...

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Bibliographische Detailangaben

Hauptverfasser:	MABON, ROSS, RAWLINS, DAVID BRENT, HARRISON, BRYCE ALDEN, RICE, DENNIS S, KIMBALL, SPENCER DAVID, VORONKOV, MICHAEL VICTOR, ZHANG, YULIAN
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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