METHODS AND COMPOSITIONS FOR THE DELIVERY OF A THERAPEUTIC AGENT

The present invention relates to a system for intranasal administration of a liquid pharmaceutical composition formulated for intranasal administration comprising: a) a nasal spray device; and b) a liquid pharmaceutical composition formulated for intranasal administration disposed in the nasal spray...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GIZURARSON SVEINBJORN, YAZDI MEHDI, GHADERI RAOUF, LUSTY MICHAEL E, ARP JAMES, PLUCINSKI GREGORY G
Format: Patent
Sprache:eng ; pol
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Beschreibung
Zusammenfassung:The present invention relates to a system for intranasal administration of a liquid pharmaceutical composition formulated for intranasal administration comprising: a) a nasal spray device; and b) a liquid pharmaceutical composition formulated for intranasal administration disposed in the nasal spray device, the liquid pharmaceutical composition comprising i) a therapeutically effective amount of a therapeutic agent that is a benzodiazepine, a pharmaceutically acceptable salt thereof or combinations thereof; and ii) a methoxy-polyethylene glycol of Formula I €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ H 3 C-O-(CH 2 CH 2 O) n -H€ƒ€ƒ€ƒ€ƒ€ƒ(I) wherein n is a number in the range of 1 to 25.