PYRIDINOYLPIPERIDINES AS 5-HT1F AGONISTS

The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	XU YAOANG, ZHANG DEYI, ZACHERL DEANNA PIATT, KOHLMAN DANIEL TIMOTHY, YING BAI-PING, COHEN MICHAEL PHILIP, MANCUSO VINCENT, VICTOR FRANTZ, LIANG SIDNEY XI
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or prevention of migraine in a mammal. The present invention also relates to a process for the synthesis of intermediates in the synthesis of compounds of Formula I.