1,5-DIPHENYL-3-BENZYLAMINO-1,5-DIHYDROPYRROLIDIN 2-ONES AS CB1 RECEPTOR MODULATORS

Compounds and pharmaceutical compositions comprising compounds of the Formula as CB1 receptor inverse agonists useful for reducing body weight in mammals, treating cognitive impairment associated with schizophrenia, and mitigating treatment emergent weight gain observed during treatment with antipsy...

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Hauptverfasser: SCHAUS, JOHN MEHNERT, KRUSHINSKI, JOSEPH HERMAN JUNIOR, TUPPER, DAVID EDWARD, KEDING, STACY JO, HU, JINGDAN, COFFEY, DAVID SCOTT
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:Compounds and pharmaceutical compositions comprising compounds of the Formula as CB1 receptor inverse agonists useful for reducing body weight in mammals, treating cognitive impairment associated with schizophrenia, and mitigating treatment emergent weight gain observed during treatment with antipsychotics.