FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION

The present invention relates to compounds of Formula I: wherein: a) represents a 6-membered heterocyclic aromatic ring in which X1 is N and X2, X3 and X4 are each independently CR''; R'' is independently H, halogen, cyano, hydroxy, C1-C3 alkyl, C1-C3 haloalkyl, cyclopropyl, C1-C...

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Hauptverfasser: RICKS MICHAEL JOHN, ROGERS RICHARD BREWER, NADER BASSAM SALIM, MORRISON IRENE MAE, YAO CHENGLIN, MIESEL JOHN LOUIS, NIYAZ NOORMOHAMED MOHAMED, GAJEWSKI ROBERT PETER, DENT WILLIAM HUNTER III, FITZPATRICK GINA MARIE, MEYER KEVIN GERALD
Format: Patent
Sprache:eng ; pol
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Zusammenfassung:The present invention relates to compounds of Formula I: wherein: a) represents a 6-membered heterocyclic aromatic ring in which X1 is N and X2, X3 and X4 are each independently CR''; R'' is independently H, halogen, cyano, hydroxy, C1-C3 alkyl, C1-C3 haloalkyl, cyclopropyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C1-C3 alkylthio, aryl, C1-C3 NHC(O)alkyl, NHC(O)H, C1-C3 haloalkylthio, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl or nitro wherein adjacent R'' substituents may form a ring; b) Z is O, S or NORZ in which RZ is H or C1-C3 alkyl; and c) A represents (i) C3-C14 cycloalkyl, containing 1 or 3 heteroatoms and 0-2 unsaturations, which may be unsubstituted or substituted with halogen, hydroxy, C1-C6 alkyl, C1-C6 haloalkyl, cyano, nitro, aroyl, aryloxy, heteroaryloxy, C1-C6 alkylthio, arylthio, heteroarylthio, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C8 acyloxy, aryl, heteroaryl, C1-C6 acyl, C1-C6 carboalkoxy or amido unsubstituted or substituted with one or two C1 -C6 alkyl groups, or (ii) C6-C14 bi- or tricyclic ring system, containing 1-3 heteroatoms and 0-2 unsaturations, which may be unsubstituted or substituted with halogen, hydroxy, C1-C6 alkyl, C1-C6 haloalkyl, cyano, nitro, aroyl, aryloxy, heteroaryloxy, C1-C6 alkylthio, arylthio, heteroarylthio, C1-C6 alkoxy, C1-C6 haloalkoxy, C1-C8 acyloxy, aryl, heteroaryl, C1-C6 acyl, C1-C6 carboalkoxy or amido unsubstituted or substituted with one or two C1-C6 alkyl groups; which are useful as antifungal agents, particularly for plants.