FERMENTATIVE PRODUCTION OF LIPSTATIN

The present invention pertains to the production of secondary metabolites and particularly to the production of lipstatin. Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases. The present invention describe...

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Bibliographische Detailangaben
Hauptverfasser:	BENICKI SVAGELJ, Neda, RASPOR, Peter, PELKO, Mitja, PETKOVIC, Hrvoje, SLADIC, Gordan, GASPARIC, Ales, FUJS, Stefan
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention pertains to the production of secondary metabolites and particularly to the production of lipstatin. Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases. The present invention describes a process allowing the production of said enzyme inhibitor in high yields and high purity.