COMBINATION OF TWO OR MORE ACTIVE INGREDIENTS USING MICROENCAPSULATED FORMULATIONS

Provided is a method of encapsulating clomazone and a second biological agent comprising: (a) mixing (i) an aqueous phase, (ii) an emulsifier and (iii) a water-immiscible phase containing clomazone, the second biological agent, and at least one first polyfunctional compound; (b) forming a dispersion of water-immiscible droplets throughout the aqueous phase; and (c) adding at least one second polyfunctional compound into the dispersion and reacting the second polyfunctional compound(s) with the first polyfunctional compound(s) to form a polymer shell around the water-immiscible droplets. Further provided is a method of preparing an agricultural composition comprising encapsulated clomazone and a second biological agent, the method comprising:(a) providing a suspension of clomazone capsules comprising solutes, diluents or carriers;(b) providing a composition of suspended particles of the second biological agent;(c) adjusting solutes, diluents or carriers in the particle suspension so that the osmolarity of the particle suspension is sufficiently like that of the capsule suspension so that the capsules are not disrupted when the suspensions of steps (a) and (b) are mixed; and(d) mixing the suspensions of steps (a) and (b).