MARKERS, METHOD FOR MANUFACTURING THEM AND THEIR APPLICATIONS

The present invention relates to labels capable of forming a covalent or non-covalent bond with a target molecule, consisting of a dye to which there is bonded in a covalent manner by one or more carbons of its chemical structure: one or more [FUNC] group(s), and optionally one or more [SOL] group(s), said label having the general formula: [DYE] representing the dye; [FUNC] each independently representing an -X-A-Z group, in which: X is chosen from the group consisting of an oxygen atom, a sulphur atom, an NR1R2 group, R1 and R2 each being independently of each other a hydrogen atom or a linear or branched C1-C30, preferably C1-C18 and more preferentially C1-C5 alkyl group; A is chosen from the group consisting of an alkylene group or an alkylene-arylene group; Z is a reactive chemical function; [SOL] each independently representing an -X′-A′-Z′ group, in which: X′ is chosen from the group consisting of an oxygen atom, a sulphur atom, an NR1R2 group, R1 and R2 each being independently of each other a hydrogen atom or a linear or branched C1-C30, preferably C1-C18 and more preferentially C1-C5 alkyl group; A′ is chosen from the group consisting of an alkylene group or an alkylene-arylene group; Z′ is a polar or apolar group.