DIRECTLY COMPRESSIBLE MATRIX FOR CONTROLLED RELEASE OF SINGLE DAILY DOSES OF CLARITHROMYCIN

The invention refers to an improved pharmaceutical formulation for controlled release of clarithromycin or its derivatives, enabled by a novel combined matrix consisting of a fatty and a hydrophilic component, whereto also a surfactant and a pH-modulator may be added when an additional influence on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FERCEJ TEMELJOTOV DARJA, SALOBIR MATEJA, OPRESNIK MARKO, MOHAR MILOJKA, REBIC LJUBOMIRA BARBARA
Format: Patent
Sprache:eng ; pol
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Beschreibung
Zusammenfassung:The invention refers to an improved pharmaceutical formulation for controlled release of clarithromycin or its derivatives, enabled by a novel combined matrix consisting of a fatty and a hydrophilic component, whereto also a surfactant and a pH-modulator may be added when an additional influence on the release profile of the active substance is desired.