4-CYCLOALKYL-SUBSTITUTED TETRAHYDROCHINOLINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS

4-CYCLOALKYL-SUBSTITUTED TETRAHYDROCHINOLINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS

The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer prote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WEBER, OLAF, WUTTKE, MARTINA, VAKALOPOULOS, ALEXANDROS, BISCHOFF, HILMAR, GIELEN-HAERTWIG, HEIKE, LI, VOLKHART, THUTEWOHL, MICHAEL, SCHMECK, CARSTEN
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.