5-(2-IMIDAZOLYNYNAMINO) BENZIMIDAZOLE DERIVATIVES, METHOD OF OBTAINING THEM AND THEIR APPLICATION AS ANTAGONISTS OF A-2-ANDRENOCEPTORS

5-(2-IMIDAZOLYNYNAMINO) BENZIMIDAZOLE DERIVATIVES, METHOD OF OBTAINING THEM AND THEIR APPLICATION AS ANTAGONISTS OF A-2-ANDRENOCEPTORS

The subject invention involves compounds having the following structure: wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; (b) R' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo; and (c) R'&...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BOGDAN SOPHIE E, CUPPS THOMAS L
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The subject invention involves compounds having the following structure: wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; (b) R' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo; and (c) R'' is selected from hydrogen, methyl, ethyl and i-propyl. The subject invention also involves pharmaceutical compositions containing such novel compounds, and the use of such compounds for preventing or treating respiratory, ocular and/or gastrointestinal disorders.