NOVEL (R)-8-FLUORO-3-N,N-SUBSTITUTED AMINO 3,4-DIHYDRO 5-CARBAMOYL-2H-1-BEZOPYRANES

NOVEL (R)-8-FLUORO-3-N,N-SUBSTITUTED AMINO 3,4-DIHYDRO 5-CARBAMOYL-2H-1-BEZOPYRANES

3-amino-5-carbamoylchromans and 8-fluoro-3-amino-5-carbamoylchromans, as well as enantiomers and salts thereof, are disclosed. Pharmaceutical compositions containing the compounds as active ingredients are also disclosed. The compounds are useful in the treatment of 5-hydroxytryptamine-mediated diso...

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Bibliographische Detailangaben
Hauptverfasser: EVENDEN JOHN L, HANSSON HANS S, THORBERG SETH O, LUNDKVIST JOHAN R.M, HAMMARBERG EVA M, JOHANSSON LARS G, ROSS SVANTE B, SOHN DANIEL D, HELLBERG SVEN E
Format: Patent
Sprache:eng ; pol
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:3-amino-5-carbamoylchromans and 8-fluoro-3-amino-5-carbamoylchromans, as well as enantiomers and salts thereof, are disclosed. Pharmaceutical compositions containing the compounds as active ingredients are also disclosed. The compounds are useful in the treatment of 5-hydroxytryptamine-mediated disorders of the central nervous system.