IMMUNOGLOBULIN BINDING HOSM

The present invention concerns immunoglobulins, such as antibodies, which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and modulate the interaction between OSM and gp130. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.

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Bibliographische Detailangaben
Hauptverfasser: PLUMPTON, CHRISTOPHER, ELLIS, JONATHAN HENRY, WEST, MICHAEL ROBERT, EON-DUVAL, ALEXANDRE, GERMASCHEWSKI, VOLKER, RAPSON, NICHOLAS TIMOTHY
Format: Patent
Sprache:eng ; pol
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Beschreibung
Zusammenfassung:The present invention concerns immunoglobulins, such as antibodies, which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and modulate the interaction between OSM and gp130. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.