Macrocyclic carboxylic acid and acylsulfonamide compound as inhibitor of HCV replication

The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infe...

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Bibliographische Detailangaben
Hauptverfasser:	ANDREWS, STEVEN WADE, KENNEDY, APRIL LAYNE, WENGLOWSKY, STEVEN MARK, WOODARD, BENJAMIN T, JIANG, YUTONG, CONDROSKI, KEVIN RONALD, MADDURU, MACHENDER R, JOSEY, JOHN ANTHONY, SEIWERT, SCOTT D, DOHERTY, GEORGE ANDREW, BLATT, LAWRENCE M, STENGEL, PETER JOHN
Format:	Patent
Sprache:	eng ; pol
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The present application provides compounds of the general formulas I-IX as defined herein, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present application further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.