METHOD OF OBTAINING NOVEL HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN AND SULFUR

The invention relates to nitrogen- and sulfur-containing heterocyclic compounds of the formula (I), wherein Ar represents an optionally mono- or polysubstituted aryl or heteroaryl group; R represents a carbonyl or (C2-6alkenyl)-carbonyl group; R represents a hydrogen atom, or a C1-6alkyl, phenyl or...

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Bibliographische Detailangaben
Hauptverfasser:	BODO MIHALY, SCHEIBER PAL, GERE ANIKO, KARPATI EGON, SARKADI ADAM, SZENTIRMAY ZSOLT, CSOMOR KATALIN, SZOMBATHELYI ZSOLT, LASZY JUDIT, NADOR KAROLY, SZPORNY LASZLO, LASZLOVSZKY ISTVAN, SZELECSENYI ERZSEBET, MOLNAR BELA, KISS BELA, PALOSI EVA, GROO DORA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to nitrogen- and sulfur-containing heterocyclic compounds of the formula (I), wherein Ar represents an optionally mono- or polysubstituted aryl or heteroaryl group; R represents a carbonyl or (C2-6alkenyl)-carbonyl group; R represents a hydrogen atom, or a C1-6alkyl, phenyl or phenyl(C1-4alkyl) group; R represents a hydrogen atom or a (C1-6 alkoxy)carbonyl group; R and R , which may be the same or different, represent a hydrogen atom or a C1-6alkyl group; R represents a hydrogen atom or a C1-6alkyl group or halophenyl group; m is 0 or 1; and n is 1 or 2, with the proviso that R is a hydrogen atom when m is 0, and acid addition salts of the compounds of formula (I) and pharmaceutical compositions thereof. The invention also relates to processes for the preparation of these compounds. The compounds of formula (I) show a significant cerebral antihypoxic activity.