NOVEL 4-CHLORO-3-SULFAMOYLBENZOIC ACID HYDRAZIDES, A PROCESS FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, THEIR USE AS MEDICAMENTS

NOVEL 4-CHLORO-3-SULFAMOYLBENZOIC ACID HYDRAZIDES, A PROCESS FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, THEIR USE AS MEDICAMENTS

The novel compounds according to the invention correspond to the general formula I in which R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms, R represen...

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Hauptverfasser: ENDRE PALOSI, GYORGY SIMON, DANDOR VIRAG, VERA GERGELLY, KATALIN MARMAROSI KELLENR, DEZSO KORBONITS, LASZIO HARSING, IDA SZVOBODA KANZEL, ERZSEBET MOLNAR BAKO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The novel compounds according to the invention correspond to the general formula I in which R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms, R represents hydrogen, an alkylthio or alkylsulphonyl group each having 1-4 carbon atoms, a straight or branched alkyl group having 1-4 carbon atoms, or a benzylthio, benzylsulphonyl, phenyl, hydroxyl or thiol group and R represents hydrogen or chlorine. The novel compounds act as diuretics and saluretics and have a hypotensive action.